Sherif F El-Khamisy Selected Research

Spinocerebellar Degenerations (Marinesco Sjogren Syndrome)

1/2018	Studying TDP1 Function in DNA Repair.
3/2014	TDP1 deficiency sensitizes human cells to base damage via distinct topoisomerase I and PARP mechanisms with potential applications for cancer therapy.
1/2013	ATM deficiency results in accumulation of DNA-topoisomerase I covalent intermediates in neural cells.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Sherif F El-Khamisy Research Topics

Disease

18	Neoplasms (Cancer) 01/2022 - 03/2014
6	Genomic Instability 11/2021 - 01/2018
5	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 03/2005
4	Nervous System Diseases (Neurological Disorders) 01/2020 - 10/2006
3	Colorectal Neoplasms (Colorectal Cancer) 01/2022 - 02/2015
3	Ovarian Neoplasms (Ovarian Cancer) 12/2021 - 01/2015
3	Hypersensitivity (Allergy) 01/2021 - 03/2014
3	Alzheimer Disease (Alzheimer's Disease) 12/2018 - 04/2016
3	Spinocerebellar Degenerations (Marinesco Sjogren Syndrome) 01/2018 - 01/2013
3	Spinocerebellar Ataxias (Spinocerebellar Ataxia) 02/2010 - 03/2005
2	Glioblastoma (Glioblastoma Multiforme) 02/2021 - 03/2014
2	Inborn Genetic Diseases (Disease, Hereditary) 09/2019 - 02/2010
2	Chromosome Breakage 12/2018 - 04/2004
2	Ataxia (Dyssynergia) 01/2018 - 05/2014
2	Early-onset ataxia with oculomotor apraxia and hypoalbuminemia 06/2009 - 03/2009
1	Huntington Disease (Huntington's Disease) 02/2022
1	Spinal Muscular Atrophy (Progressive Muscular Atrophy) 01/2022
1	Motor Neuron Disease (Primary Lateral Sclerosis) 01/2022
1	Hyperthermia 05/2021
1	Glioma (Gliomas) 02/2021
1	Hypoxia (Hypoxemia) 01/2021
1	Renal Cell Carcinoma (Grawitz Tumor) 03/2020
1	Rhabdomyosarcoma 12/2018
1	Melanoma (Melanoma, Malignant) 10/2018
1	Acute Promyelocytic Leukemia 09/2018
1	Leukemia 09/2018
1	Infections 06/2017
1	Mitochondrial Diseases (Mitochondrial Disease) 04/2017
1	Cardiotoxicity 01/2017
1	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 07/2014
1	Seizures (Absence Seizure) 05/2014
1	Intellectual Disability (Idiocy) 05/2014
1	Ataxia Telangiectasia (Louis Bar Syndrome) 01/2013
1	Neuroblastoma 05/2007

Drug/Important Bio-Agent (IBA)

19	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 04/2004
9	Proteins (Proteins, Gene)FDA Link 01/2022 - 04/2004
5	tyrosyl-DNA phosphodiesteraseIBA 12/2018 - 02/2010
4	Type I DNA Topoisomerases (Topoisomerase I)IBA 02/2022 - 02/2010
4	EnzymesIBA 11/2021 - 02/2010
4	PoisonsIBA 05/2021 - 07/2014
4	Biomarkers (Surrogate Marker)IBA 01/2019 - 02/2015
3	taxaneIBA 12/2021 - 01/2015
3	A-Form DNA (A-DNA)IBA 02/2021 - 05/2007
3	RNA (Ribonucleic Acid)IBA 01/2021 - 06/2017
2	MicroRNAs (MicroRNA)IBA 12/2021 - 01/2015
2	Paclitaxel (Taxol)FDA LinkGeneric 12/2021 - 07/2018
2	Transcription Factors (Transcription Factor)IBA 10/2021 - 01/2021
2	Phosphoric Diester Hydrolases (Phosphodiesterases)IBA 05/2021 - 03/2005
2	Temozolomide (Temodar)FDA LinkGeneric 02/2021 - 03/2014
2	Pharmaceutical PreparationsIBA 02/2021 - 01/2017
2	Nucleic AcidsIBA 09/2019 - 01/2018
2	Irinotecan (Camptosar)FDA LinkGeneric 01/2017 - 02/2015
2	Adenosine Monophosphate (AMP)IBA 06/2009 - 03/2009
1	RNA Polymerase I (Polymerase I, RNA)IBA 01/2022
1	PlatinumIBA 01/2022
1	Ribosomal DNA (rDNA)IBA 01/2022
1	EndonucleasesIBA 11/2021
1	Histones (Histone)IBA 10/2021
1	DipeptidesIBA 08/2021
1	Small Interfering RNA (siRNA)IBA 02/2021
1	Messenger RNA (mRNA)IBA 02/2021
1	Biological ProductsIBA 01/2021
1	DNA HelicasesIBA 01/2021
1	NucleosidesIBA 01/2020
1	nasIBA 09/2019
1	Melanins (Melanin)IBA 10/2018
1	Histone Deacetylase 1IBA 09/2018
1	Retinoic Acid Receptors (Retinoic Acid Receptor)IBA 09/2018
1	trans-sodium crocetinate (crocetin)IBA 09/2018
1	SofosbuvirIBA 09/2018
1	Antiviral Agents (Antivirals)IBA 09/2018
1	GoldIBA 01/2018
1	Free RadicalsIBA 04/2017
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2017
1	Phosphotransferases (Kinase)IBA 01/2017
1	Harmine (Telepathine)IBA 01/2017
1	CamptothecinIBA 01/2016
1	2- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA 01/2016
1	Peptides (Polypeptides)IBA 02/2015
1	Topotecan (Hycamtin)FDA LinkGeneric 07/2014
1	Indicators and Reagents (Reagents)IBA 07/2014
1	Alkylating AgentsIBA 03/2014
1	Deoxyribonuclease I (Nickase)IBA 03/2014
1	Protein Kinases (Protein Kinase)IBA 04/2004

Therapy/Procedure

13	Therapeutics 01/2022 - 03/2014
3	Drug Therapy (Chemotherapy) 05/2021 - 07/2014
2	Radiotherapy 05/2021 - 03/2020
2	Ligation 03/2009 - 10/2006
1	Aftercare (After-Treatment) 09/2018